Rekombinanter Integrin beta 7 Antikörper
Kurzübersicht für Rekombinanter Integrin beta 7 Antikörper (ABIN7072353)
Target
Alle Integrin beta 7 (ITGB7) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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                                            Verwendungszweck
- Anti-Integrin beta-7 [FIB504], Rabbit IgG, kappa
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                                            Spezifität
- FIB504 recognizes an epitope on intergin beta-7 subunit that overlaps completely with the epitope defined by Fib27 and Fib30, and also partially with the epitope defined by FIB21 and FIB22. In the mouse beta-7 is selectively found on the majority of mature lymphocytes, whereas a small subpopulation of thymocytes and bone marrow cells express beta-7. Beta-7 is also expressed in variable amounts in CD4 T memory cells. Integrin molecules mediate cell-cell and cell-extracellular matrix adhesion and are involved in lymphocyte homing, leukocyte recruitment to inflammatory sites, myogenesis, hemopoiesis, and melanoma metastasis.
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                                            Kreuzreaktivität
- Maus
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                                            Produktmerkmale
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                        Original Species of Ab: Rat Original Format of Ab: IgG2a 
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                                            Aufreinigung
- Protein A affinity purified
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                                            Immunogen
- FIB504 was prepared by immunizing rats with TK1 cells.
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                                            Isotyp
- IgG kappa
 
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                                            Applikationshinweise
- FIB504 can be used for IF, FC and can block TKI cell aggregation and beta-7 intergrin-mediated cell adhesion.
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                                            Kommentare
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                        This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques. 
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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                                            Konzentration
- 1 mg/mL
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                                            Buffer
- PBS with 0.02 % Proclin 300.
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                                            Konservierungsmittel
- ProClin
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                                            Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            Lagerung
- 4 °C,-20 °C
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                                            Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
 
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    - Integrin beta 7 (ITGB7)
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                                            Andere Bezeichnung
- Integrin beta-7
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                                            Hintergrund
- FIB-27, FIB 27, Fib-27, Fib27, Fib 27, fib27, fib-27, fib 27, Integrin b7, integrin b-7, ITGB7, Gut homing receptor beta subunit
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                                            UniProt
- P26011
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                                            Pathways
- Integrin Complex
 Target
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