Rekombinanter Integrin beta 7 Antikörper

Produktnummer ABIN7072353

Dieses Anti-Integrin beta 7-Antikörper ist ein Kaninchen Chimeric-Antikörper zur Detektion von Integrin beta 7 in FACS, IF und BR. Geeignet für Human und Maus.

Kurzübersicht für Rekombinanter Integrin beta 7 Antikörper (ABIN7072353)

Target: Integrin beta 7 (ITGB7)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser Integrin beta 7 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Blocking Reagent (BR)

Klon: FIB504

Produktdetails anti-Integrin beta 7 Antikörper

Verwendungszweck: Anti-Integrin beta-7 [FIB504], Rabbit IgG, kappa

Spezifität: FIB504 recognizes an epitope on intergin beta-7 subunit that overlaps completely with the epitope defined by Fib27 and Fib30, and also partially with the epitope defined by FIB21 and FIB22. In the mouse beta-7 is selectively found on the majority of mature lymphocytes, whereas a small subpopulation of thymocytes and bone marrow cells express beta-7. Beta-7 is also expressed in variable amounts in CD4 T memory cells. Integrin molecules mediate cell-cell and cell-extracellular matrix adhesion and are involved in lymphocyte homing, leukocyte recruitment to inflammatory sites, myogenesis, hemopoiesis, and melanoma metastasis.

Kreuzreaktivität: Maus

Produktmerkmale:

Original Species of Ab: Rat

Original Format of Ab: IgG2a

Aufreinigung: Protein A affinity purified

Immunogen: FIB504 was prepared by immunizing rats with TK1 cells.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: FIB504 can be used for IF, FC and can block TKI cell aggregation and beta-7 intergrin-mediated cell adhesion.

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu Integrin beta 7

Target: Integrin beta 7 (ITGB7)

Andere Bezeichnung: Integrin beta-7

Hintergrund: FIB-27, FIB 27, Fib-27, Fib27, Fib 27, fib27, fib-27, fib 27, Integrin b7, integrin b-7, ITGB7, Gut homing receptor beta subunit

UniProt: P26011

Pathways: Integrin Complex