Rekombinanter L-Selectin Antikörper

Produktnummer ABIN7072350

Dieses Anti-L-Selectin-Antikörper ist ein Kaninchen Chimeric-Antikörper zur Detektion von L-Selectin in FACS, WB, IP und BP. Geeignet für Human, Rind (Kuh) und Schimpanse.

Kurzübersicht für Rekombinanter L-Selectin Antikörper (ABIN7072350)

Target: L-Selectin (SELL) (Selectin L (SELL))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Rind (Kuh), Schimpanse

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser L-Selectin Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Blocking Peptide (BP)

Klon: DREG-56

Produktdetails anti-L-Selectin Antikörper

Verwendungszweck: Anti-CD62L [DREG-56], Rabbit IgG, kappa

Spezifität: This antibody is specific for human L-selectin, a homing receptor selectively expressed on lymphocytes, which allows their entry into secondary lymphoid tissues via high endothelial venules.

Kreuzreaktivität: Schimpanse, Rind (Kuh)

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Aufreinigung: Protein A affinity purified

Immunogen: This antibody was produced by immunizing mice with the concentrated supernatant generated after centrifugation of human peripheral blood leukocytes.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: This antibody has been used in WB, IP and binding assays to define a lymphocyte homing receptor for PLN HEVs (Kishimoto, 1990). In vitro, this antibody has been shown to specifically inhibit over 90 % of binding of human lymphocytes to HEVs within frozen sections of peripheral, but not mucosal, lymphoid tissue (Kishimoto, 1990). This antibody has also been used in labelling studies to demonstate that the trophectoderm of implantation-competent human embryos expresses L-selectin (Genbacev, 2003).

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu L-Selectin

Target: L-Selectin (SELL) (Selectin L (SELL))

Andere Bezeichnung: CD62L

Hintergrund: L-selectin, LECAM-1, Ly-22, MEL-14, CD62 antigen-like family member L, Leukocyte adhesion molecule 1, LAM-1, Leukocyte-endothelial cell adhesion molecule 1, LECAM1, Lymph node homing receptor, Lymphocyte antigen 22, Lymphocyte surface MEL-14 antigen

UniProt: P14151