Rekombinanter CD147 Antikörper

Produktnummer ABIN7072342

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD147 in ELISA und BR. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Rekombinanter CD147 Antikörper (ABIN7072342)

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD147 Antikörper ist unkonjugiert

Applikation: ELISA, Blocking Reagent (BR)

Klon: Ab-1

Produktdetails anti-CD147 Antikörper

Verwendungszweck: Anti-Basigin [Ab-1], Mouse IgG1, kappa

Spezifität: The antibody binds to basigin with an affinity (Kd) of 4 nM reported for the original antibody.

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Aufreinigung: Protein A affinity purified

Immunogen: Recombinant ectodomains of human basigin.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: The antibody binds specifically to basigin, a protein of the immunoglobulin superfamily which is expressed on the surface of erythrocyte and acts as a receptor for the human malaria parasite P. falciparum. The recombinant chimeric monoclonal antibody Ab-1 acts by blocking the interaction between basigin and PfRH5, a ligand necessary for the P. falciparum erythrocyte invasion, thereby inhibiting the development of malaria.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu CD147

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Andere Bezeichnung: Basigin

Hintergrund: CD147, BSG, Cluster of differentiation 147, Extracellular matrix metalloproteinase inducer, EMMPRIN, 5F7, Collagenase stimulatory factor, Leukocyte activation antigen M6, Tumor cell-derived collagenase stimulatory factor, TCSF

UniProt: P35613

Pathways: S100 Proteine