Rekombinanter Discoidin Domain Receptor 1 (Extracellular Domain) Antikörper

Produktnummer ABIN7072320

Der Kaninchen Chimeric anti-Discoidin Domain Receptor 1 Antikörper (Klon 3E3) (ABIN7072320) detektiert spezifisch Discoidin Domain Receptor 1 in BP, ELISA und WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter Discoidin Domain Receptor 1 (Extracellular Domain) Antikörper (ABIN7072320)

Target: Discoidin Domain Receptor 1

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Unkonjugiert

Applikation: Blocking Peptide (BP), ELISA, Western Blotting (WB)

Klon: 3E3

Produktdetails

Bindungsspezifität: Extracellular Domain

Verwendungszweck: Anti-Discoidin Domain Receptor 1 [3E3], Rabbit IgG, kappa

Spezifität: This antibody binds specifically to the extracellular domain of human DDR1.

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG2

Aufreinigung: Protein A affinity purified

Immunogen: Recombinant human DDR1 extracellular domain.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: This antibody binds to human Discoidin Domain Receptor 1, a receptor tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates the attachemnt of the cell to the extracellular matrix. This receptor is required for blastocyst implantation during pregnancy, mammary gland differentiation as well as lactation. It promotes smooth muscle cell migration as well as tumour cell invasion. The antibody acts as an antagonist.

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Antigendetails

Target: Discoidin Domain Receptor 1

Hintergrund: DDR1

UniProt: Q08345