Rekombinanter Paxillin (LD2 Motif) (AA 141-156) Antikörper

Produktnummer ABIN7072305

Der Maus Monoklonal anti-Paxillin (LD2 Motif) Antikörper (Klon LD2 sAB) (ABIN7072305) detektiert spezifisch Paxillin (LD2 Motif) in ELISA und WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter Paxillin (LD2 Motif) (AA 141-156) Antikörper (ABIN7072305)

Target: Paxillin (LD2 Motif)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Klon: LD2 sAB

Produktdetails

Bindungsspezifität: AA 141-156

Verwendungszweck: Anti-Paxillin (LD2 Motif) [LD2 sAB], Mouse IgG1, kappa

Spezifität: The antibody binds specifically to the LD-2 motif of human paxillin with a Kd of 24 nM.

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: scFv

Aufreinigung: Protein A affinity purified

Immunogen: Peptide corresponding to paxillin-LD2 motif (residues 141-156) fused to MBP, peptide sequence: NLSELDRLLLELNAVQHNP.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: This antibody binds to the LD2-motif of human paxillin, a signal transduction adaptor protein involved in focal adhesion, with binding partners including integrins, Src, FAK or actin complexes. The antibody inhibits complex formation between paxillin and FAK. Paxillin is involved in both inside-out cell signalling and outside-to-inside cell signalling.

Kommentare:

This full-length, reformatted mouse antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Antigendetails

Target: Paxillin (LD2 Motif)

Hintergrund: PXN

UniProt: P49023