Rekombinanter Paxillin (LD4 Motif) (AA 260-278) Antikörper

Produktnummer ABIN7072303

Dieser Maus Monoklonal Antikörper detektiert spezifisch Paxillin (LD4 Motif) in ELISA und WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter Paxillin (LD4 Motif) (AA 260-278) Antikörper (ABIN7072303)

Target: Paxillin (LD4 Motif)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Klon: LD4 sAB

Produktdetails

Bindungsspezifität: AA 260-278

Verwendungszweck: Anti-Paxillin (LD4 Motif) [LD4 sAB], Mouse IgG1, kappa

Spezifität: The antibody binds specifically to the LD-4 motif of human paxillin with a Kd of 6 nM.

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: scFv

Aufreinigung: Protein A affinity purified

Immunogen: Peptide corresponding to human paxillin-LD4 motif (residues 260-278) fused to MBP, peptide sequence: WGGSATRELDELMASLSD.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: This antibody binds to the LD4-motif of human paxillin, a signal transduction adaptor protein involved in focal adhesion, with binding partners including integrins, Src, FAK or actin complexes. The antibody inhibits complex formation between paxillin and FAK. Paxillin is involved in both inside-out cell signalling and outside-to-inside cell signalling.

Kommentare:

This full-length, reformatted mouse antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Antigendetails

Target: Paxillin (LD4 Motif)

Hintergrund: PXN

UniProt: P49023