Rekombinanter CD28 Antikörper

Produktnummer ABIN7072237

Dieses Kaninchen Chimeric-Antikörper erkennt spezifisch CD28 in FACS, IHC, SPR, CoSt und Agon. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für Rekombinanter CD28 Antikörper (ABIN7072237)

Target: CD28

Antikörpertyp: Recombinant Antibody

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser CD28 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC), Surface Plasmon Resonance (SPR), Co-Stimulation (CoSt), Agonist (Agon)

Klon: D665

Produktdetails anti-CD28 Antikörper

Verwendungszweck: Anti-CD28 [D665], Rabbit IgG, kappa

Spezifität: This antibody binds to the laterally exposed C'D loop of CD28 and induces T cell proliferation without TCR ligation.

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Aufreinigung: Protein A affinity purified

Immunogen: The original D665 antibody was generated by immunizing mice alternately with A20 cells expressing mCD28 i.p. and with recombinant mCD28Ig s.c.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: This antibody binds to mouse CD28. The original mouse IgG1 version was shown to trigger T-cell proliferation in vitro and in vivo in a TCR-independent manner and is a superagonistic antibody. This antibody does not compete with E18 (Ab00286).

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu CD28

Target: CD28

Andere Bezeichnung: CD28

Hintergrund: TP44, T-cell-specific surface glycoprotein CD28, TP44

UniProt: P31041

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response