Rekombinanter Bax (Active Monomer) (AA 12-24), (AA 3-16) Antikörper
Kurzübersicht für Rekombinanter Bax (Active Monomer) (AA 12-24), (AA 3-16) Antikörper (ABIN7072202)
Target
Antikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 3-16, AA 12-24
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Verwendungszweck
- Anti-Bax (active monomer) [6A7], Rabbit IgG, kappa
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Spezifität
- In the presence of nonionic detergent, the antibody avidly binds the monomeric form of Bax, but not Bax complexed with either Bcl-XL or Bcl-2. [6A7 ] Bax antibody only recognizes conformationally changed active Bax.
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Kreuzreaktivität
- Maus, Ratte
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Produktmerkmale
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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Aufreinigung
- Protein A affinity purified
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Immunogen
- KLH conjugated to peptides corresponding to amino acids 3-16 of murine Bax (CGSGEQLGSGGPTSS), amino acids 3-16 of human Bax (CGSGEQPRGGGPTSS), and amino acids 12-24 shared by Bax from both species (CGPTSSEQIMKTGA).
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Isotyp
- IgG kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG1 format, for improved compatibility with existing reagents, assays and techniques.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Bax (Active Monomer)
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Hintergrund
- Bcl-2-like protein 4, Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4
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UniProt
- Q07812
Target
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