UTS2R Antikörper (AA 154-167)

Produktnummer ABIN7043874

Dieses Anti-UTS2R-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von UTS2R in WB und IHC. Geeignet für Ratte.

Kurzübersicht für UTS2R Antikörper (AA 154-167) (ABIN7043874)

Target: UTS2R (Urotensin 2 Receptor (UTS2R))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UTS2R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-UTS2R Antikörper

Bindungsspezifität: AA 154-167

Verwendungszweck: A Rabbit Ployclonal Antibody to Urotensin II Receptor

Spezifität: 2nd intracellular loop

Homologie: Bovine - identical, human,canine - 13,14 amino acid residues identical

Produktmerkmale: Anti-Urotensin II Receptor Antibody is directed against the 2nd cytoplasmic loop of the rat UTS2R. Anti-Urontenisn II Receptor Antibody (ABIN7043874 and ABIN7044242) can be used in western blot and immunohistochemical applications, and recognizes UTS2R in rat samples.

Aufreinigung: Affinity purified on immobilized antigen.

Immunogen:

Immunogen: Synthetic peptide

Immunogen Sequence: (C)RPLDTVQRSKGYRK, corresponding to amino acid residues 154-167 of rat URIIR

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Antigen preadsorption control: 1 μg peptide per 1 μg antibody

Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A

Application Dilutions Western blot wb: 1:200

Kommentare:

Cited Application: IHC

Negative Control: (ABIN7237551)

Blocking Peptide: (ABIN7237551)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 0.2 mL double distilled water (DDW).

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Details zu UTS2R

Target: UTS2R (Urotensin 2 Receptor (UTS2R))

Andere Bezeichnung: UTS2R

Hintergrund: Urotensin 2 receptor, UR-II-R, UR2R, UTS2R, SENR, GPR14,Urotensin II is a powerful vasoconstrictive substance. The human urotensin II receptor (UR-II-R) was originally isolated as an orphan receptor (GPR14) from neural and sensory tissues.1,2 Urotensin II is expressed in various human tissues such as the CNS, skeletal muscle, smooth muscle, pancreas, and heart.3-5 Binding of urotensin II to the receptor leads to activation of phospholipase C. The resulting increase in intracellular Ca2+ may cause the contraction of vascular smooth muscle. ERK1/2 phophorylation may also be involved in mediating the biological activities of urotensin II.6 Recently, evidence has accumulated indicating that urotensin II is also expressed in various kinds of tumor cells such as adrenal tumors and neuroblastomas. In those cells, urotensin II was reported to stimulate cell growth.7-9

Alternative names: Urotensin II Receptor, Urotensin 2 receptor, UR-II-R, UR2R, UTS2R, SENR, GPR14

Gen-ID: 57305

NCBI Accession: NM_018949

UniProt: P49684