SNCG Antikörper (AA 96-108)

Produktnummer ABIN7043802

Dieses Anti-SNCG-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SNCG in WB, IHC und IF. Geeignet für Ratte.

Kurzübersicht für SNCG Antikörper (AA 96-108) (ABIN7043802)

Target: SNCG (Synuclein, gamma (Breast Cancer-Specific Protein 1) (SNCG))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNCG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-SNCG Antikörper

Bindungsspezifität: AA 96-108

Verwendungszweck: A Rabbit Polyclonal Antibody to Gamma-Synuclein

Spezifität: C-terminus

Kreuzreaktivität: Maus, Ratte

Kreuzreaktivität (Details): Not recommended for use with human samples.

Homologie: Mouse - identical

Produktmerkmale: Anti-Gamma-Synuclein Antibody (ABIN7043802, ABIN7045184 and ABIN7045185) is a highly specific antibody directed against an epitope of the rat protein. It can be used in western blot analysis. It has been designed to recognize γ-Synuclein from mouse and rat samples. The antibody will not recognize the protein from human samples.

Aufreinigung: Affinity purified on immobilized antigen.

Immunogen:

Immunogen: Synthetic peptide

Immunogen Sequence: (C)RKEDLEPPAQDQE, corresponding to amino acid residues 96 - 108 of rat gamma-Synuclein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Antigen preadsorption control: 1 μg peptide per 1 μg antibody

Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:200

Application Dilutions Western blot wb: 1:200

Kommentare:

Negative Control: (ABIN7237365)

Blocking Peptide: (ABIN7237365)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 0.2 mL double distilled water (DDW).

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Details zu SNCG

Target: SNCG (Synuclein, gamma (Breast Cancer-Specific Protein 1) (SNCG))

Andere Bezeichnung: SNCG

Hintergrund: γ-Synuclein, Breast Cancer-Specific Gene 1 Protein, BCSG1, Persyn, Synoretin, SNCG,γ-synuclein is a 127 amino acids protein that belongs to the synuclein family of proteins. Synucleins are natively unfolded proteins, i.e. they have no secondary or tertiary structure in solution and hence these proteins are heat stable. The unusual biophysical properties of synucleins are rooted in their characteristic primary sequence that includes a highly conserved N-terminal domain with an 11- residue repeat and a less conserved acidic C-terminal domain that contains many proline residues1.Mammalian γ-synuclein, encoded by BCSG1 (breast cancer specific gene 1), was discovered in a screen for breast cancer markers2. It is expressed in the peripheral nervous system in primary sensory neurons, sympathetic neurons, and motor neurons. It is also detected in the brain3, olfactory epithelium and breast/ovarian tumors4. Indeed, exogenous expression of this protein increases the invasive and metastatic potential of breast tumors5.The roles of synucleins are not fully elucidated but this group of conserved and unusual proteins contributes to diverse disease processes spanning neurodegenerative disease and cancer and hence, studying the synucleins specific cellular activity is very tempting and promising.

Alternative names: γ-Synuclein, Breast Cancer-Specific Gene 1 Protein, BCSG1, Persyn, Synoretin, SNCG

Gen-ID: 64347

NCBI Accession: NM_001330120

UniProt: O76070