Synapsin III Antikörper (Extracellular)

Produktnummer ABIN7043788

Produktdetails anti-Synapsin III Antikörper

Target: Synapsin III (SYN3)

Bindungsspezifität: AA 510-523, Extracellular

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Synapsin III Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Verwendungszweck: A Rabbit Polyclonal Antibody to Synapsin III

Spezifität: Extracellular, C-terminus

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Mouse,human - identical

Produktmerkmale: Anti-Synapsin III (SYN3) Antibody (ABIN7043788, ABIN7044664 and ABIN7044665)) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize Synapsin III from human, rat, and mouse samples.

Aufreinigung: Affinity purified on immobilized antigen.

Immunogen:

Immunogen: Synthetic peptide

Immunogen Sequence: (C)RPPVQGRSTSQQGE, corresponding to amino acid residues 510-523 of rat Synapsin III

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Antigen preadsorption control: 1 μg peptide per 1 μg antibody

Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:200

Application Dilutions Western blot wb: 1:200-1:400

Kommentare:

Negative Control: BLP-NR017

Blocking Peptide: BLP-NR017

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 0.2 mL double distilled water (DDW).

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Details zu Synapsin III

Target: Synapsin III (SYN3)

Andere Bezeichnung: SYN3 (SYN3 Produkte)

Hintergrund: Synapsin-3,Synapsin 3 (Syn3) belongs to the synapsin family of neuronal phosphoproteins, vesicle-associated proteins that includes two additional members: Synapsin I and Synapsin II. Alternative splicing of the genes results in at least ten variants with various levels of homology.Synapsins are involved in synaptogenesis, synaptic transmission and synaptic plasticity and are required for the formation and maintenance of the reserve and recycling pools of synaptic vesicles through association with the actin cytoskeleton. Several protein kinases, including PKA, calcium-calmodulin regulated protein kinases and the mitogen-activated protein kinase (MAPK) use synapsins as their substrates1-4.Syn3 plays an important role in several disorders, including bipolar disorder, schizophrenia and epilepsy1.

Alternative names: Synapsin III (SYN3), Synapsin-3

Gen-ID: 29130

NCBI Accession: NM_001135774

UniProt: O70441