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Synapsin III Antikörper (Extracellular)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Synapsin III in WB, IHC und IF. Er zeigt eine Reaktivität gegenüber Ratte.
Produktnummer ABIN7043788

Kurzübersicht für Synapsin III Antikörper (Extracellular) (ABIN7043788)

Target

Alle Synapsin III (SYN3) Antikörper anzeigen
Synapsin III (SYN3)

Reaktivität

  • 16
  • 7
  • 7
  • 3
  • 2
  • 2
  • 2
  • 1
Ratte

Wirt

  • 16
  • 5
  • 1
Kaninchen

Klonalität

  • 19
  • 3
Polyklonal

Konjugat

  • 17
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Synapsin III Antikörper ist unkonjugiert

Applikation

  • 22
  • 12
  • 9
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • Bindungsspezifität

    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 510-523, Extracellular

    Verwendungszweck

    A Rabbit Polyclonal Antibody to Synapsin III

    Spezifität

    Extracellular, C-terminus

    Kreuzreaktivität

    Human, Maus, Ratte

    Homologie

    Mouse,human - identical

    Produktmerkmale

    Anti-Synapsin III (SYN3) Antibody (ABIN7043788, ABIN7044664 and ABIN7044665) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize Synapsin III from human, rat, and mouse samples.

    Aufreinigung

    Affinity purified on immobilized antigen.

    Immunogen

    Immunogen: Synthetic peptide

    Immunogen Sequence: (C)RPPVQGRSTSQQGE, corresponding to amino acid residues 510-523 of rat Synapsin III

    Isotyp

    IgG
  • Applikationshinweise

    Antigen preadsorption control: 1 μg peptide per 1 μg antibody

    Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:200

    Application Dilutions Western blot wb: 1:200-1:400

    Kommentare

    Negative Control: (ABIN7237315)

    Blocking Peptide: (ABIN7237315)

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    0.2 mL double distilled water (DDW).

    Konzentration

    1 mg/mL

    Buffer

    PBS pH 7.4

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

    Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

  • Target

    Synapsin III (SYN3)

    Andere Bezeichnung

    SYN3

    Hintergrund

    Synapsin-3,Synapsin 3 (Syn3) belongs to the synapsin family of neuronal phosphoproteins, vesicle-associated proteins that includes two additional members: Synapsin I and Synapsin II. Alternative splicing of the genes results in at least ten variants with various levels of homology.Synapsins are involved in synaptogenesis, synaptic transmission and synaptic plasticity and are required for the formation and maintenance of the reserve and recycling pools of synaptic vesicles through association with the actin cytoskeleton. Several protein kinases, including PKA, calcium-calmodulin regulated protein kinases and the mitogen-activated protein kinase (MAPK) use synapsins as their substrates1-4.Syn3 plays an important role in several disorders, including bipolar disorder, schizophrenia and epilepsy1.

    Alternative names: Synapsin III (SYN3), Synapsin-3

    Gen-ID

    29130

    NCBI Accession

    NM_001135774

    UniProt

    O70441
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