SSTR1 Antikörper (Extracellular, N-Term)

Produktnummer ABIN7887136

Der Kaninchen Polyklonal anti-SSTR1 Antikörper (ABIN7887136) detektiert spezifisch SSTR1 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Ratte.

Kurzübersicht für SSTR1 Antikörper (Extracellular, N-Term) (ABIN7887136)

Target: SSTR1 (Somatostatin Receptor 1 (SSTR1))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SSTR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-SSTR1 Antikörper

Bindungsspezifität: AA 26-40, Extracellular, N-Term

Verwendungszweck: A Rabbit Polyclonal Antibody to Somatostatin Receptor Type 1

Kreuzreaktivität: Maus, Ratte

Homologie: Mouse - identical, human - 13,15 amino acid residues identical

Produktmerkmale: Anti-Somatostatin Receptor Type 1 (extracellular) Antibody (ABIN7043763 and ABIN7045262) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize SSTR1 from rat, mouse, and human samples.

Aufreinigung: Affinity purified on immobilized antigen.

Immunogen: CSRGPGSGAADGMEE, corresponding to amino acid residues 26-40 of rat SSTR1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

WB: 1:200

FC: The optimal concentration should be determined by the user

ICC: The optimal concentration should be determined by the user

IHC: 1:1000

IP: The optimal concentration should be determined by the user

Kommentare:

Negative Control: (ABIN7237232)

Blocking Peptide: (ABIN7237232)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.

Konzentration: 0.8 mg/mL

Buffer: PBS pH 7.4, 1 % BSA with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Details zu SSTR1

Target: SSTR1 (Somatostatin Receptor 1 (SSTR1))

Andere Bezeichnung: SSTR1

Hintergrund:

Synonyms: SSTR1, SS1R, SRIF-2, SRIF2A

Description: Somatostatin is a small cyclic peptide that is widely expressed throughout the central nervous system and peripheral tissues.1 In peripheral tissues, somatostatin exerts inhibitory effects on secretion processes, whereas in the brain it acts as a neurotransmitter in both a stimulatory and inhibitory manner.1,2Somatostatin mediates its action via six high affinity G-protein coupled receptors (SSTR1, SSTR2a, SSTR2b, SSTR3, SSTR4 and SSTR5) which are encoded by five genes.1,2 Expression of the different receptors is developmentally regulated in a time and tissue-specific manner.2Somatostatin receptors have been found on a variety of neuroendocrine tumors, such as paragangliomas, carcinoids and breast tumors.3 Synthetic peptide derivatives of somatostatin have been successfully used in the treatment of neuroendocrine malignancies and in in vivo imaging of tumors that are positive to somatostatin receptors.4

Gen-ID: 25033

NCBI Accession: NM_001049

UniProt: P28646