KCNK15 Antikörper (Extracellular)

Produktnummer ABIN7043445

Produktdetails anti-KCNK15 Antikörper

Target: KCNK15 (Potassium Channel Subfamily K Member 15 (KCNK15))

Bindungsspezifität: AA 43-57, Extracellular

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNK15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: A Rabbit Polyclonal Antibody to KCNK15 Channel

Spezifität: 1st extracellular loop

Kreuzreaktivität: Maus, Ratte

Kreuzreaktivität (Details): Not recommended for human samples

Homologie: Mouse - identical

Produktmerkmale: Anti-KCNK15 (TASK-5) (extracellular) Antibody is directed against an epitope of the rat KCNK15 channel. Anti-KCNK15 (TASK-5) (extracellular) Antibody (ABIN7043445, ABIN7045054 and ABIN7045055)) can be used in western blot analysis. The antibody recognizes an extracellular epitope and is thus ideal for detecting the channel in living cells. It has been designed to recognize KCNK15 from rat and mouse samples. The antibody will unlikely recognize the channel from human samples.

Aufreinigung: Affinity purified on immobilized antigen.

Immunogen:

Immunogen: Synthetic peptide

Immunogen Sequence: (C)RKRGEFRRKYRFSAD, corresponding to amino acid residues 43-57 of rat KCNK15 

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Antigen preadsorption control: 1 μg peptide per 1 μg antibody

Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A

Application Dilutions Western blot wb: 1:200

Kommentare:

Negative Control: BLP-PC158

Blocking Peptide: BLP-PC158

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 0.2 mL double distilled water (DDW).

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Details zu KCNK15

Target: KCNK15 (Potassium Channel Subfamily K Member 15 (KCNK15))

Andere Bezeichnung: KCNK15 (KCNK15 Produkte)

Hintergrund: Potassium channel subfamily K member 15, Acid-sensitive K+ channel protein TASK-5, TWIK-related acid-sensitive K+ channel 5, K2P15.1,TASK1-5 are members of the two-pore domain K+ channels. They have four transmembrane domains and assist in setting the resting membrane potential.TASK5 (K2P15.1, KCNK15) was identified using the TASK-3 sequence in a GenBank search. However, when expressed in COS-7 cells, it does not form a functional K+ current1.The channel is distributed in the brain, heart, lung, kidney, liver, pancreas, adrenal gland and placenta2.

Alternative names: KCNK15 (TASK-5), Potassium channel subfamily K member 15, Acid-sensitive K+ channel protein TASK-5, TWIK-related acid-sensitive K+ channel 5, K2P15.1

Gen-ID: 156873

NCBI Accession: NM_022358

UniProt: Q8R5I0