Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

NPTXR Antikörper (Extracellular)

NPTXR Reaktivität: Maus WB, IHC, IF (cc), LCI Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7043370
  • Target Alle NPTXR Antikörper anzeigen
    NPTXR (Neuronal Pentraxin Receptor (NPTXR))
    Bindungsspezifität
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 162-176, Extracellular
    Reaktivität
    • 13
    • 4
    • 3
    Maus
    Wirt
    • 12
    • 2
    • 1
    Kaninchen
    Klonalität
    • 16
    Polyklonal
    Konjugat
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    Dieser NPTXR Antikörper ist unkonjugiert
    Applikation
    • 15
    • 13
    • 10
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (Cultured Cells) (IF (cc)), Live Cell Imaging (LCI)
    Verwendungszweck
    A Rabbit Polyclonal Antibody to NPTXR (extracellular)
    Spezifität
    Extracellular, C-terminus
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Rat - identical, human - 14 out of 15 amino acid residues identical
    Produktmerkmale
    Anti-Neuronal Pentraxin Receptor (NPTXR)(extracellular) Antibody (ABIN7043370, ABIN7044746 and ABIN7044747)) is a highly specific antibody directed against an extracellular epitope of the mouse NPTXR. The antibody can be used in western blot and immunohistochemistry. It has been designed to recognize NPTXR from mouse, rat and human samples.
    Aufreinigung
    Affinity purified on immobilized antigen.
    Immunogen

    Immunogen: Synthetic peptide

    Immunogen Sequence: (C)RGLQDAGPRRDTMAD, corresponding to amino acid residues 162 - 176 of mouse NPTXR

    Isotyp
    IgG
    Top Product
    Discover our top product NPTXR Primärantikörper
  • Applikationshinweise

    Antigen preadsorption control: 1 μg peptide per 1 μg antibody

    Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:1200

    Application Dilutions Western blot wb: 1:400

    Kommentare

    Negative Control: BLP-NR193

    Blocking Peptide: BLP-NR193

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    0.2 mL double distilled water (DDW).
    Konzentration
    1 mg/mL
    Buffer
    PBS pH 7.4
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung

    Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

    Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

  • Target
    NPTXR (Neuronal Pentraxin Receptor (NPTXR))
    Andere Bezeichnung
    NPTXR (NPTXR Produkte)
    Hintergrund
    NPR, NPTXR,Neuronal Pentraxin Receptor (NPTXR) belongs to the Pentraxin superfamily of proteins (NP) that is characterized by a pentraxin domain at the C-terminal end. It is the only pentraxin family member anchored to the cell membrane by a putative N-terminal transmembrane domain, as opposed to the other two family members, Neuronal Pentraxin1 (NP1) and Neuronal Pentraxin 2 (NP2) that are secreted proteins. NPs can form homo pentamers and hetero pentamers via their pentraxin domains 1.NPTXR was first identified as the receptor for the snake venom toxin taipoxin and was later found to bind to AMPARs at excitatory synapses and play important, roles in the activity-dependent regulation of neural circuits via this binding activity 1.Lately, the levels of NPTXR protein in cerebrospinal fluid has been identified as a novel potential biomarker of Alzheimer's disease progression and could have important utility in assessing treatment success in clinical trials 2. In addition, NPTXR was identified as a molecule required for gastric cancer metastasis 3.

    Alternative names: NPR
    Gen-ID
    73340
    NCBI Accession
    NM_014293
    UniProt
    Q99J85
Sie sind hier:
Kundenservice