NPTXR Antikörper (Extracellular)

Produktnummer ABIN7043370

Dieses Anti-NPTXR-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NPTXR in WB, IHC, FACS und LCI. Geeignet für Maus.

Kurzübersicht für NPTXR Antikörper (Extracellular) (ABIN7043370)

Target: NPTXR (Neuronal Pentraxin Receptor (NPTXR))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NPTXR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Live Cell Imaging (LCI)

Produktdetails anti-NPTXR Antikörper

Bindungsspezifität: AA 162-176, Extracellular

Verwendungszweck: A Rabbit Polyclonal Antibody to NPTXR (extracellular)

Spezifität: Extracellular, C-terminus

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Rat - identical, human - 14 out of 15 amino acid residues identical

Produktmerkmale: Anti-Neuronal Pentraxin Receptor (NPTXR)(extracellular) Antibody (ABIN7043370, ABIN7044746 and ABIN7044747) is a highly specific antibody directed against an extracellular epitope of the mouse NPTXR. The antibody can be used in western blot and immunohistochemistry. It has been designed to recognize NPTXR from mouse, rat and human samples.

Aufreinigung: Affinity purified on immobilized antigen.

Immunogen:

Immunogen: Synthetic peptide

Immunogen Sequence: (C)RGLQDAGPRRDTMAD, corresponding to amino acid residues 162 - 176 of mouse NPTXR

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Antigen preadsorption control: 1 μg peptide per 1 μg antibody

Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:1200

Application Dilutions Western blot wb: 1:400

Kommentare:

Negative Control: (ABIN7236082)

Blocking Peptide: (ABIN7236082)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 0.2 mL double distilled water (DDW).

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Details zu NPTXR

Target: NPTXR (Neuronal Pentraxin Receptor (NPTXR))

Andere Bezeichnung: NPTXR

Hintergrund: NPR, NPTXR,Neuronal Pentraxin Receptor (NPTXR) belongs to the Pentraxin superfamily of proteins (NP) that is characterized by a pentraxin domain at the C-terminal end. It is the only pentraxin family member anchored to the cell membrane by a putative N-terminal transmembrane domain, as opposed to the other two family members, Neuronal Pentraxin1 (NP1) and Neuronal Pentraxin 2 (NP2) that are secreted proteins. NPs can form homo pentamers and hetero pentamers via their pentraxin domains 1.NPTXR was first identified as the receptor for the snake venom toxin taipoxin and was later found to bind to AMPARs at excitatory synapses and play important, roles in the activity-dependent regulation of neural circuits via this binding activity 1.Lately, the levels of NPTXR protein in cerebrospinal fluid has been identified as a novel potential biomarker of Alzheimer's disease progression and could have important utility in assessing treatment success in clinical trials 2. In addition, NPTXR was identified as a molecule required for gastric cancer metastasis 3.

Alternative names: NPR

Gen-ID: 73340

NCBI Accession: NM_014293

UniProt: Q99J85