NMUR1 Antikörper (Extracellular)

Produktnummer ABIN7043365

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch NMUR1 in WB, FACS, IHC und LCI. Er zeigt eine Reaktivität gegenüber Ratte.

Kurzübersicht für NMUR1 Antikörper (Extracellular) (ABIN7043365)

Target: NMUR1 (Neuromedin U Receptor 1 (NMUR1))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NMUR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Live Cell Imaging (LCI)

Produktdetails anti-NMUR1 Antikörper

Bindungsspezifität: AA 316-331, Extracellular

Verwendungszweck: A Rabbit Polyclonal antibody to NMUR1 (extracellular)

Spezifität: Extracellular, 3rd loop.

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Human - 12 out of 16 amino acid residues identical, Mouse - 10 out of 16 amino acid residues identical

Produktmerkmale: A rabbit polyclonal antibody to NMUR1 (extracellular)

Aufreinigung: Affinity purified on immobilized antigen.

Immunogen:

Immunogen: Synthetic peptide

Immunogen Sequence: (C)DRLMWSMVSHWTDGLR, corresponding to amino acid residues 316 - 331 of rat NMUR1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Antigen preadsorption control: 1 μg peptide per 1 μg antibody

Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:300

Application Dilutions Western blot wb: 1:400-1:500

Kommentare:

Negative Control: (ABIN7236064)

Blocking Peptide: (ABIN7236064)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Details zu NMUR1

Target: NMUR1 (Neuromedin U Receptor 1 (NMUR1))

Andere Bezeichnung: NMUR1

Hintergrund: Neuromedin-U Receptor 1, G Protein-Coupled Receptor 66, GPR66,Neuromedin U Receptor 1 (NMUR1) is one of the two receptors for the neuropeptide Neuromedin U (NMU). NMUR1 and the second receptor NMUR2 are members of the G protein coupled receptors (GPCRs) superfamily 1.NMU is a neuropeptide with potent activity on smooth muscles that is widely distributed in the gut and central nervous system. NMU interaction with one of its two receptors- NMU1R or NMU2R, mediates the stimulation of smooth muscles, increase of blood pressure, alteration of ion transport in the gut, control of local blood flow and regulation of adrenocortical function1-2.NMU1R is abundantly expressed in peripheral tissues including lung, GI tract, pancreatic islets, testis, adipose, immune tissues, and dorsal root ganglia2, and due to its diverse functions it is a very appealing drug and research candidate.

Alternative names: Neuromedin-U Receptor 1, G Protein-Coupled Receptor 66, GPR66

Gen-ID: 65276

NCBI Accession: NM_006056

UniProt: Q9JJI5