Netrin 1 Antikörper (Secreted)
Kurzübersicht für Netrin 1 Antikörper (Secreted) (ABIN7043349)
Target
Alle Netrin 1 (NTN1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 181-195, Secreted
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Verwendungszweck
- A Rabbit Polyclonal Antibody to Netrin-1
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Spezifität
- Secreted
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Kreuzreaktivität
- Human, Maus, Ratte
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Homologie
- Mouse,human - identical
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Produktmerkmale
- Anti-Netrin-1 Antibody (ABIN7043349, ABIN7044726 and ABIN7044727) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot analysis. It has been designed to recognize Netrin-1 from human, mouse, and rat samples.
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Aufreinigung
- Affinity purified on immobilized antigen.
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Immunogen
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Immunogen: Synthetic peptide
Immunogen Sequence: CRKMYNRPHRAPITK, corresponding to amino acid residues 181 - 195 of rat Netrin-1
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Isotyp
- IgG
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Applikationshinweise
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:300
Application Dilutions Western blot wb: 1:200
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Kommentare
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Negative Control: (ABIN7236010)
Blocking Peptide: (ABIN7236010)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- 0.2 mL double distilled water (DDW).
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Konzentration
- 1 mg/mL
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Buffer
- PBS pH 7.4
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- Netrin 1 (NTN1)
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Andere Bezeichnung
- NTN1
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Hintergrund
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NTN1, MRMV4,Netrins are a family comprised of five members: three secreted proteins (netrins 1, 3 and 4), and two glycosylphosphatidylinositol (GPI)-anchored membrane proteins, netrins G1 and G21. Netrin-1 is a diffusible long-range axonal guidance cue expressed in floor plate cells of the central nervous system. It is secreted in order to direct exons to their target1-3. Axon guidance by netrin-1 is implicated in multiple developing brain regions and developing neuronal types. It also plays a role in axon branching, synaptogenesis, cell migration, cell survival, and axon regeneration4.
Alternative names: NTN1, MRMV4 -
Gen-ID
- 114523
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NCBI Accession
- NM_004822
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UniProt
- Q924Z9
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Pathways
- Regulation of Cell Size
Target
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