KISS1R Antikörper (3rd Extracellular Loop)

Produktnummer ABIN7886526

Der Kaninchen Polyklonal anti-KISS1R Antikörper wird verwendet zum Nachweis von KISS1R in Proben von Human. Er wurde validiert für WB, IHC, IF, FACS und LCI.

Kurzübersicht für KISS1R Antikörper (3rd Extracellular Loop) (ABIN7886526)

Target: KISS1R (KISS1 Receptor (KISS1R))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KISS1R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Live Cell Imaging (LCI)

Produktdetails anti-KISS1R Antikörper

Bindungsspezifität: 3rd Extracellular Loop, AA 292-305

Verwendungszweck: A Rabbit Polyclonal Antibody to Kisspeptin Receptor

Kreuzreaktivität: Human, Ratte

Homologie: mouse - 12,14 amino acid residues identical,Rat - 13

Produktmerkmale: Anti-KISS1 Receptor (GPR54) (extracellular) Antibody (ABIN7043294, ABIN7044548 and ABIN7044549) is a highly specific antibody directed against an epitope of the human kisspeptin receptor. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize KISS1R from human, rat, and mouse samples.

Aufreinigung: Affinity purified on immobilized antigen.

Immunogen: (C)GSWHPRSYAAYALK, corresponding to amino acid residues 292-305 of human KISS1R

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

WB: 1:500

FC: The optimal concentration should be determined by the user

ICC: The optimal concentration should be determined by the user

IHC: 1:100

IP: The optimal concentration should be determined by the user

Kommentare:

Cited Application: IHC|ICC

Negative Control: (ABIN7235833)

Blocking Peptide: (ABIN7235833)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.

Konzentration: 0.8 mg/mL

Buffer: PBS pH 7.4, 1 % BSA with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Details zu KISS1R

Target: KISS1R (KISS1 Receptor (KISS1R))

Andere Bezeichnung: KISS1R

Hintergrund:

Synonyms: Kisspeptin receptor, KISS1R, Metastin receptor, AXOR12

Description: The kisspeptin receptor (KISS1R, GPCR54) is a member of the G-protein coupled receptor superfamily. KISS1R natural ligands are peptides called kisspeptins which are encoded by the Kiss1 gene. The Kiss1 gene was originally discovered by Hershey scientists who named it after their famous chocolate, the "Kiss".The kisspeptins, acting through KISS1R, were found to be potent inhibitors of metastasis in a variety of cancer cell types including thyroid and pancreatic cancer cells. KISS1R and kisspeptins are involved in the direct regulation of the reproductive neuroendocrine axis.KISS1R is widely distributed throughout the brain, where it is most highly expressed in the hypothalamic and amygdaloid nuclei. High expression was also found in the pancreas and placenta. Lower-level expression was found in a variety of other peripheral tissues including peripheral blood leukocytes, kidney, lung, testes, spleen, thymus, adrenal glands and lymph nodes.1-3

Gen-ID: 84634

NCBI Accession: NM_032551

UniProt: Q969F8