Galanin Receptor 1 Antikörper (1st Extracellular Loop)

Produktnummer ABIN7886411

Der Kaninchen Polyklonal anti-Galanin Receptor 1 Antikörper wird verwendet zum Nachweis von Galanin Receptor 1 in Proben von Maus. Er wurde validiert für WB, IF, IHC und IC.

Kurzübersicht für Galanin Receptor 1 Antikörper (1st Extracellular Loop) (ABIN7886411)

Target: Galanin Receptor 1 (GALR1)

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Galanin Receptor 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunochromatography (IC)

Produktdetails anti-Galanin Receptor 1 Antikörper

Bindungsspezifität: 1st Extracellular Loop, AA 60-71

Verwendungszweck: A Rabbit Polyclonal Antibody to Galanin Receptor Type 1

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Rat,human - identical

Produktmerkmale: Anti-GALR1 Antibody (ABIN7043180 and ABIN7044397) is a highly specific antibody directed against an epitope of the mouse Galanin receptor 1. The antibody can be used in western blot, immunohistochemistry, and immunocytochemistry applications. It has been designed to recognize GALR1 from mouse, rat, and human samples.

Aufreinigung: Affinity purified on immobilized antigen.

Immunogen: RSKPGKPRSTTN(C), corresponding to amino acid residues 60-71 of mouse Galanin receptor type 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

WB: 1:200

FC: The optimal concentration should be determined by the user

ICC: 1:100

IHC: 1:200

IP: The optimal concentration should be determined by the user

Kommentare:

Negative Control: (ABIN7235473)

Blocking Peptide: (ABIN7235473)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.

Konzentration: 0.8 mg/mL

Buffer: PBS pH 7.4, 1 % BSA with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Details zu Galanin Receptor 1

Target: Galanin Receptor 1 (GALR1)

Andere Bezeichnung: GALR1

Hintergrund:

Synonyms: Galanin receptor type 1, GALNR1, GAL1R

Description: Galanin is a neuropeptide, consisting of 29-30 amino acid residues, involved in the regulation of cognition, mood, feeding, seizure activity and pain. Galanin exerts its action via three known receptors, the Galanin receptor type 1 (GALR1), Galanin receptor type 2 (GALR2) and Galanin receptor type 3 (GALR3). The Galanin receptors belong to the G-protein coupled receptor superfamily.1-4Based on mRNA, the GALR1 is predominantly distributed in the central nervous system, spinal cord and dorsal root ganglia while GALR2 is abundant in both central and peripheral nervous systems. GALR3 mRNA is distributed in peripheral tissues such as the heart, spleen, and testis. However, its expression in the brain is still controversial.4,5

Gen-ID: 14427

NCBI Accession: NM_001480

UniProt: P56479

Pathways: cAMP Metabolic Process