AQP9 Antikörper (Intracellular, N-Term)

Produktnummer ABIN7887076

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch AQP9 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Ratte.

Kurzübersicht für AQP9 Antikörper (Intracellular, N-Term) (ABIN7887076)

Target: AQP9 (Aquaporin 9 (AQP9))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AQP9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-AQP9 Antikörper

Bindungsspezifität: AA 4-19, Intracellular, N-Term

Verwendungszweck: A Rabbit Polyclonal Antibody to Aquaporin 9 Channel

Kreuzreaktivität: Maus, Ratte

Kreuzreaktivität (Details): Unlikely to recognize human samples.

Homologie: Mouse - 13,16 amino acid residues identical

Produktmerkmale: Anti-Aquaporin 9 Antibody (ABIN7042945 and ABIN7045206) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize AQP9 from mouse and rat samples.

Aufreinigung: Affinity purified on immobilized antigen.

Immunogen: (C)EKDGAKKSLMQRLALK, corresponding to amino acid residues 4-19 of rat AQP9

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

WB: 1:200

FC: The optimal concentration should be determined by the user

ICC: The optimal concentration should be determined by the user

IHC: 1:100

IP: The optimal concentration should be determined by the user

Kommentare:

Cited Application: IHC

Negative Control: (ABIN7234783)

Blocking Peptide: (ABIN7234783)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.

Konzentration: 0.8 mg/mL

Buffer: PBS pH 7.4, 1 % BSA with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Details zu AQP9

Target: AQP9 (Aquaporin 9 (AQP9))

Andere Bezeichnung: AQP9

Hintergrund:

Synonyms: AQP9, Aquaglyceroporin-9

Description: Aquaporin 9 (AQP-9) belongs to a family of membrane proteins that allow passage of water and certain other solutes through biological membranes.1 The family is composed of 13 members (AQP-0 to AQP-12). Little is known about the function of the two newest members, AQP-11 and AQP-12.The aquaporins can be divided into two functional groups based on their permability characteristics: the aquaporins that are permeated primarily by water (AQP-1, AQP-2, AQP4, AQP-5, AQP-6, AQP-8), and the aquaglyceroporins that are permeated by water and other small solutes such as glycerol. This last group includes AQP-3, AQP-7, AQP-9 and AQP-10.The proteins present a conserved structure of six transmembrane domains with intracellular N- and C-termini. The functional channel is a tetramer but each subunit has a separate pore and therefore the functional channel unit contains four pores.2AQP-9 is expressed in several tissues including the brain, liver, testis and spleen. In the liver AQP-9 has a central role in glycerol metabolism as demonstrated in experiments using AQP-9 knockout mice: mice deficient in AQP-9 expression showed enhanced plasma levels of glycerol and triglycerides.3

Gen-ID: 65054

NCBI Accession: NM_020980

UniProt: P56627