RAE1 Antikörper (AA 101-200)

Produktnummer ABIN704171

Produktdetails anti-RAE1 Antikörper

Target: RAE1 (RAE1 RNA Export 1 Homolog (S. Pombe) (RAE1))

Bindungsspezifität: AA 101-200

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAE1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RAE1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu RAE1

Target: RAE1 (RAE1 RNA Export 1 Homolog (S. Pombe) (RAE1))

Andere Bezeichnung: RAE1 (RAE1 Produkte)

Synonyme: gle2 antikoerper, mig14 antikoerper, mnrp41 antikoerper, mrnp41 antikoerper, MRNP41 antikoerper, zgc:56449 antikoerper, zgc:77723 antikoerper, 3230401I12Rik antikoerper, 41 antikoerper, D2Ertd342e antikoerper, MNRP antikoerper, MNRP41 antikoerper, MIG14 antikoerper, Mnrp41 antikoerper, dJ481F12.3 antikoerper, dJ800J21.1 antikoerper, ribonucleic acid export 1 antikoerper, RAE1 RNA export 1 homolog antikoerper, ribonucleic acid export 1 L homeolog antikoerper, rae1 antikoerper, LOC664096 antikoerper, RAE1 antikoerper, rae1.L antikoerper, Rae1 antikoerper

Hintergrund:

Synonyms: RAE-1, MIG 14, MIG14, Mnrp 41, Mnrp41, mRNA associated protein mrnp 41, mRNA binding protein 41 kD, mRNA export protein, MRNP 41, MRNP41, RAE 1, RAE1 RNA export 1 S.pombe homolog, RAE1 homolog, Rae1 protein homolog, RAE1 RNA export 1 homolog, RNA export 1, RNA export 1 homolog, Homolog of yeast Rae1 mRNA associated protein of 41 kDa. RAE1L_HUMAN

Background: Mutations in Rae1 and Gle2(Saccharomyces cerevisae homolog) genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Depletion of Rae1 from extracts or cells severely inhibits mitotic spindle assembly. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Gen-ID: 8480

Pathways: SARS-CoV-2 Protein Interaktom