FPR2 Antikörper (AA 51-150)

Produktnummer ABIN702175

Produktdetails anti-FPR2 Antikörper

Target: FPR2 (Formyl Peptide Receptor 2 (FPR2))

Bindungsspezifität: AA 51-150

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FPR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))

Spezifität: Possible cross-reactivity with FPR1

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FPRL1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-FPR2 Antikörper (ABIN702175)

Diao, Zhang, Chen, Yuan, Lee, Geng, Kowalski, Guo, Xiong, Li, Li: "Deficiency in Toll-interacting protein (Tollip) skews inflamed yet incompetent innate leukocytes in vivo during DSS-induced septic colitis." in: Scientific reports, Vol. 6, pp. 34672, (2016) (PubMed).

Details zu FPR2

Target: FPR2 (Formyl Peptide Receptor 2 (FPR2))

Andere Bezeichnung: FPRL1/Lipoxin A4 receptor (FPR2 Produkte)

Synonyme: ALXR antikoerper, FMLP-R-II antikoerper, FMLPX antikoerper, FPR2A antikoerper, FPRH1 antikoerper, FPRH2 antikoerper, FPRL1 antikoerper, HM63 antikoerper, LXA4R antikoerper, E330010I07Rik antikoerper, Fpr-rs2 antikoerper, Fprl1 antikoerper, ALX antikoerper, Fpr-rs1 antikoerper, Fpr-s1 antikoerper, LXA4-R antikoerper, Lxa4r antikoerper, FMLP-R-I antikoerper, FPR2 antikoerper, formyl peptide receptor 2 antikoerper, formyl peptide receptor 3 antikoerper, N-formyl peptide receptor 2 antikoerper, FPR2 antikoerper, Fpr2 antikoerper, Fpr3 antikoerper, LOC100444626 antikoerper

Hintergrund:

Synonyms: ALXR, HM63, FMLPX, FPR2A, FPRH1, FPRH2, FPRL1, LXA4R, FMLP-R-II, N-formyl peptide receptor 2, FMLP-related receptor I, FMLP-R-I, Formyl peptide receptor-like 1, Lipoxin A4 receptor, LXA4 receptor, RFP, FPR2

Background: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).

Gen-ID: 2358

UniProt: P25090