Mu Opioid Receptor 1 Antikörper (Opioid Receptor, mu 1) (AA 180-230)

Details for Product anti-OPRM1 Antibody No. ABIN701755
Antigen
  • LMOR
  • M-OR-1
  • MOP
  • MOR
  • MOR1
  • OPRM
  • MOP-R
  • MOR-1
  • MOR-1O
  • Oprm
  • mor
  • muOR
  • MORA
  • Oprrm1
  • or2
  • ZFOR2
  • OPRM1
  • opioid receptor mu 1
  • opioid receptor, mu 1
  • outer membrane protein OprM
  • OPRM1
  • Oprm1
  • oprm1
  • oprM1
Epitop
AA 180-230
40
15
13
10
8
8
8
8
4
4
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
134
70
55
10
8
8
3
3
2
2
1
1
1
1
1
1
Wirt
Kaninchen
137
3
3
Klonalität
Polyklonal
Konjugat
Dieser Mu Opioid Receptor 1 Antikörper ist unkonjugiert
6
5
4
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
95
56
49
30
17
13
8
6
5
2
1
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human mu Opioid receptor
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere Mu Opioid Receptor 1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung mu Opioid Receptor (OPRM1 Antibody Abstract)
Hintergrund

This gene encodes one of at least three opioid receptors in humans, the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503.2:c.118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene. Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains. [provided by RefSeq, Oct 2013]

Subcellular location: Extracellular, Helical

Synonyms: MOP, MOR, LMOR, MOR1, OPRM, M-OR-1, Mu-type opioid receptor, MOR-1, Mu opiate receptor, Mu opioid receptor, hMOP, OPRM1

Gen-ID 4988
UniProt P35372
Pathways cAMP Metabolic Process, Synaptic Membrane
Applikations-hinweise WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Opioid Receptor, mu 1 (OPRM1) (AA 180-230) antibody (ABIN701755) Formalin-fixed and paraffin embedded mouse hindfoot tumor labeled with Anti-°-Opioid ...
Immunohistochemistry (IHC) image for anti-Opioid Receptor, mu 1 (OPRM1) (AA 180-230) antibody (ABIN701755) Formalin-fixed and paraffin embedded mouse skin labeled with Anti-°-Opioid receptor P...
Produkt verwendet in: Wu, Li, Wu: "The effect of chronic intermittent hypoxia on respiratory sensitivity to morphine in rats." in: Sleep & breathing = Schlaf & Atmung, Vol. 21, Issue 1, pp. 227-233, 2017 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB), Western Blotting (WB) (Probematerial (Species): Rat (Rattus)). Weitere Details: Sample: medullas

Laureano, Dalle Molle, Alves, Luft, Desai, Ross, Silveira: "Intrauterine growth restriction modifies the hedonic response to sweet taste in newborn pups - Role of the accumbal μ-opioid receptors." in: Neuroscience, Vol. 322, pp. 500-8, 2016 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Rat (Rattus)). Weitere Details: Sample: Brain

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