ITGA5 Antikörper

Produktnummer ABIN7013949

Produktdetails anti-ITGA5 Antikörper

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser ITGA5 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Functional Studies (Func)

Spezifität: The rat monoclonal antibody 5H10-27 (MFR5) recognizes an extracellular epitope of murine CD49e, a 135 kDa protein serving as VLA-5 alpha chain, expressed on thymocytes, activated T cells, splenic B cells, and mast cells.

Aufreinigung: Purified by protein-G affinity chromatography.

Immunogen: C57BL/6 x A/J)F1 murine mast cell line

Klon: 5H10-27 (MFR5)

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 1-4 μg/mL.
Functional application: Blocking

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4

Konservierungsmittel: Azide free

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu ITGA5

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Andere Bezeichnung: CD49e (ITGA5 Produkte)

Synonyme: ITGA5 antikoerper, Cd49e antikoerper, Fnra antikoerper, VLA5 antikoerper, CD49e antikoerper, FNRA antikoerper, VLA5A antikoerper, Itga5_retired antikoerper, integrin subunit alpha 5 antikoerper, integrin alpha 5 (fibronectin receptor alpha) antikoerper, ITGA5 antikoerper, Itga5 antikoerper

Hintergrund: Integrin alpha 5,CD49e, the alpha 5 integrin, noncovalently associates with the beta 1integrin (CD29) to form VLA-5 integrin complex. CD49e itself is composed of two disulfide-linked chains of 135 kDa and 25 kDa. VLA-5 binds to RGD sequence of fibronectin, and to neural adhesion molecule L1. It is important in maintaining the integrity of endothelial monolayers, in monocyte migration into the extracellular tissues, and it also provides a co-stimulatory signal to T cells and enhances receptor and complement receptor-mediated phagocytosis.,ITGA5, VLA-5 alpha, FNRA

Gen-ID: 16402

UniProt: P11688

Pathways: Integrin Complex