CD51/CD61 Antikörper

Produktnummer ABIN7013947

Der Maus Monoklonal Anti-CD51/CD61-Antikörper wurde für FACS, IP und IHC (fro) validiert. Er ist geeignet, CD51/CD61 in Proben von Human und Huhn zu detektieren.

Kurzübersicht für CD51/CD61 Antikörper (ABIN7013947)

Target: CD51/CD61 (ITGAV/ITGB3) (Integrin alpha V, Integrin beta 3 (ITGAV/ITGB3))

Reaktivität: Human, Huhn

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD51/CD61 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: 23C6

Produktdetails anti-CD51/CD61 Antikörper

Verwendungszweck: Anti-Hu CD51/CD61 Purified

Spezifität: The mouse monoclonal antibody 23C6 recognizes an extracellular epitope on CD51/CD61 complex, that is expressed mainly on human osteoclasts, but also e.g. on placenta, or melanoma cell lines. The epitope is native and sensitive to fixation. In chicken this antibody can be used to selectively identify the thrombocytes.

Keine Kreuzreaktivität: Rind (Kuh), Schwein, Kaninchen

Aufreinigung: Purified by protein-A affinity chromatography.

Immunogen: A cell suspension containing osteoclasts from osteoclastomas

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 2-6 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu CD51/CD61

Target: CD51/CD61 (ITGAV/ITGB3) (Integrin alpha V, Integrin beta 3 (ITGAV/ITGB3))

Andere Bezeichnung: CD51/CD61

Hintergrund: CD51/CD61 (integrin alpha5beta3), also known as osteoclast functional antigen, serves as a vitronectin receptor, and binds also to fibronectin, fibrinogen, thrombospondin, osteopontin, collagen, and von Willebrand factor. Expression of this antigen increases with melanoma progression. In healthy individuals CD51/CD61 is expressed mainly on osteoclasts, placenta, and endothelial cells, at lower levels on platelets and macrophages.,VNRA, MSK8, ITGB3, ITGAV, Integrin alpha5beta3, OFA, VR