ITGA4 Antikörper

Produktnummer ABIN7013910

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch ITGA4 in FACS, IP, IHC (fro) und Func. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für ITGA4 Antikörper (ABIN7013910)

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser ITGA4 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Klon: DATK32

Produktdetails anti-ITGA4 Antikörper

Verwendungszweck: Anti-Ms LPAM-1 Purified Azide Free

Spezifität: The rat monoclonal antibody DATK32 recognizes an extracellular epitope of integrin alpha 4 (CD49d) and integrin beta7 (Ly69) components of mouse LPAM-1 complex, which is expressed on the majority of peripheral lymphocytes, as well as on subsets of thymocytes and bone marrow cells.

Aufreinigung: Purified by protein-G affinity chromatography.

Immunogen: TK1 cells

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Functional application: Blocking of cell adhesion.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4

Konservierungsmittel: Azide free

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu ITGA4

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Andere Bezeichnung: LPAM-1

Hintergrund: Integrin alpha 4 / beta 7 (CD49d / Ly69) , also known as LPAM-1 (Llmphocyte Peyer´s patch adhesion molecule 1), is a heterodimeric (150 kDa / 130 kDa) integrin complex which mediates lymphocyte homing to Peyer´s patch high endothelial venules and to the intestinal lamina propria. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. Ligands of LPAM-1 are MAdCAM-1, VCAM-1, and fibronectin, but the alpha 4 subunit (CD49d) can mediate also homotypic adhesion.,Integrin alpha 4 beta 7, CD49d / Ly69

Pathways: Integrin Complex