PKC Antikörper (pSer660)

Produktnummer ABIN7265230

Produktdetails anti-PKC Antikörper

Target: PKC (PKC pan) (Protein Kinase C (pan) (PKC pan))

Bindungsspezifität: pSer660

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: Phosphorylated antibody

Aufreinigung: Affinity purification

Immunogen: A phospho specific peptide corresponding to residues surrounding Ser660 of human PKC (pan) betaII

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PKC

Target: PKC (PKC pan) (Protein Kinase C (pan) (PKC pan))

Andere Bezeichnung: PKC (PKC pan Produkte)

Synonyme: PKC antikoerper, PKCI antikoerper, Prkc antikoerper, Prkcc antikoerper, RATPKCI antikoerper, protein kinase C, gamma antikoerper, Prkcg antikoerper

Hintergrund: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.

Molekulargewicht:

Observed_MW: 95 kDa

Calculated_MW: 59 kDa/67 kDa/74- 83 kDa

Gen-ID: 5578, 5579, 5580

UniProt: P17252, P05771, Q05655, Q02156, P24723, Q04759

Pathways: Positive Regulation of Response to DNA Damage Stimulus