Cofilin Antikörper (pSer3)
Kurzübersicht für Cofilin Antikörper (pSer3) (ABIN7265124)
Target
Alle Cofilin (CFL1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer3
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Produktmerkmale
- Phosphorylated antibody
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Aufreinigung
- Affinity purification
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Immunogen
- A phospho specific peptide corresponding to residues surrounding S3 of human CFL1
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000 IHC 1:50-1:100 IF 1:100-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Cofilin (CFL1) (Cofilin 1 (CFL1))
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Andere Bezeichnung
- CFL1
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Hintergrund
- The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH -dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH -dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
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Molekulargewicht
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Observed_MW: 18 kDa
Calculated_MW: 18 kDa
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Gen-ID
- 1072
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UniProt
- P23528
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Pathways
- Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
Target
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