PBXIP1 Antikörper

Produktnummer ABIN7264696

Dieser Anti-PBXIP1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von PBXIP1 in WB. Geeignet für Human, Maus und Ratte.

Kurzübersicht für PBXIP1 Antikörper (ABIN7264696)

Target: PBXIP1 (Pre-B-Cell Leukemia Homeobox Interacting Protein 1 (PBXIP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PBXIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PBXIP1 Antikörper

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human PBXIP1 (NP_065385.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PBXIP1

Target: PBXIP1 (Pre-B-Cell Leukemia Homeobox Interacting Protein 1 (PBXIP1))

Andere Bezeichnung: PBXIP1

Hintergrund: The protein encoded by this gene interacts with the PBX1 homeodomain protein, inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein, which is primarily cytosolic but can shuttle to the nucleus, also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer, brain tumors, and lung cancer. Several transcript variants encoding different isoforms have been found for this gene. More variants exist, but their full-length natures have yet to be determined.

Molekulargewicht:

Observed_MW: 110 kDa

Calculated_MW: 72 kDa/77 kDa/80 kDa

Gen-ID: 57326

UniProt: Q96AQ6