HIRA Antikörper
Kurzübersicht für HIRA Antikörper (ABIN7264499)
Target
Alle HIRA Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein of human HIRA (NP_003316.3).
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Isotyp
- IgG
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anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (AA 250-550) antibody
HIRA Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) antibodyHIRA Reaktivität: Human ELISA, FACS Wirt: Maus Monoclonal 5B6 unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (AA 1-1017) antibodyHIRA Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (pThr555) antibodyHIRA Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (AA 32-61), (N-Term) antibodyHIRA Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB36757 unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) antibodyHIRA Reaktivität: Human ICC, DB Wirt: Maus Monoclonal 374C6a unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) antibodyHIRA Reaktivität: Human WB Wirt: Kaninchen Monoclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (AA 251-350) antibodyHIRA Reaktivität: Maus WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (AA 431-461) antibodyHIRA Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB13843 unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) antibodyHIRA Reaktivität: Saccharomyces cerevisiae WB Wirt: Maus Monoclonal 4B9 unconjugated
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Applikationshinweise
- WB 1:500-1:2000 IHC 1:100-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))
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Andere Bezeichnung
- HIRA
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Hintergrund
- This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.
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Molekulargewicht
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Observed_MW: 112 kDa
Calculated_MW: 89 kDa/111 kDa
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Gen-ID
- 7290
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UniProt
- P54198
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Pathways
- Chromatin Binding
Target
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