Cofilin 2 Antikörper
Kurzübersicht für Cofilin 2 Antikörper (ABIN7264069)
Target
Alle Cofilin 2 (CFL2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein of human CFL2 (NP_068733.1).
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000 IF 1:50-1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Cofilin 2 (CFL2)
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Andere Bezeichnung
- CFL2
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Hintergrund
- This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH -dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.
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Molekulargewicht
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Observed_MW: 18 kDa
Calculated_MW: 16 kDa/18 kDa
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Gen-ID
- 1073
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UniProt
- Q9Y281
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Pathways
- Caspase Kaskade in der Apoptose
Target
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