Der Kaninchen Polyklonal anti-ZAK Antikörper (ABIN7263385) detektiert spezifisch ZAK in IF und IHC.
Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
ZAK
(Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))
Andere Bezeichnung
ZAK
Hintergrund
This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.