BTNL2 Antikörper

Produktnummer ABIN7263105

Der Kaninchen Polyklonal Anti-BTNL2-Antikörper wurde für WB validiert. Er ist geeignet, BTNL2 in Proben von Human und Maus zu detektieren.

Kurzübersicht für BTNL2 Antikörper (ABIN7263105)

Target: BTNL2 (Butyrophilin-Like 2 (MHC Class II Associated) (BTNL2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BTNL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BTNL2 Antikörper

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human BTNL2 (NP_062548.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu BTNL2

Target: BTNL2 (Butyrophilin-Like 2 (MHC Class II Associated) (BTNL2))

Andere Bezeichnung: BTNL2

Hintergrund: This gene encodes a major histocompatibility complex, class II associated, type I transmembrane protein which belongs to the butyrophilin-like B7 family of immunoregulators. It is thought to be involved in immune surveillance, serving as a negative T-cell regulator by decreasing T-cell proliferation and cytokine release. The encoded protein contains an N-terminal signal peptide, two pairs of immunoglobulin-like domains, separated by a heptad peptide sequence, and a C-terminal transmembrane domain. Naturally occurring mutations in this gene are associated with sarcoidosis, rheumatoid arthritis, ulcerative colitis, inflammatory bowel disease, myositis, type 1 diabetes, systemic lupus erythematosus, acute coronary syndrome, and prostate cancer.

Molekulargewicht:

Observed_MW: 60 kDa

Calculated_MW: 19 kDa/27 kDa/28 kDa/30 kDa/43 kDa/50 kDa

Gen-ID: 56244

UniProt: Q9UIR0