COMT Antikörper
Kurzübersicht für COMT Antikörper (ABIN7010982)
Target
Alle COMT Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein of human COMT (NP_009294.1).
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Isotyp
- IgG
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anti-Catechol-O-Methyltransferase (COMT) (Internal Region) antibody
Verified COMT Reaktivität: Human WB, IHC, ELISA Wirt: Ziege Polyclonal unconjugated
anti-Catechol-O-Methyltransferase (COMT) (N-Term) antibodyVerified COMT Reaktivität: Human WB, ELISA, FACS Wirt: Ziege Polyclonal unconjugated
anti-Catechol-O-Methyltransferase (COMT) antibodyKO Validated COMT Reaktivität: Human WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Catechol-O-Methyltransferase (COMT) (AA 52-271) antibodyCOMT Reaktivität: Human, Ratte, Maus WB, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Catechol-O-Methyltransferase (COMT) (AA 1-182) antibodyCOMT Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 1G4-1A1 unconjugated
anti-Catechol-O-Methyltransferase (COMT) (AA 26-141) antibodyCOMT Reaktivität: Ratte, Maus WB, IF, BI Wirt: Maus Monoclonal 4-COMT unconjugated
anti-Catechol-O-Methyltransferase (COMT) (AA 52-271) antibodyCOMT Reaktivität: Human WB, IHC, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Catechol-O-Methyltransferase (COMT) (Internal Region) antibodyCOMT Reaktivität: Human, Ratte, Maus, Affe, Rind (Kuh), Schwein, Fledermaus IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Catechol-O-Methyltransferase (COMT) (C-Term) antibodyCOMT Reaktivität: Human IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Catechol-O-Methyltransferase (COMT) antibodyKD Validated COMT Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 23GB3735 unconjugated Recombinant Antibody
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Applikationshinweise
- IHC 1:50-1:200 IF 1:50-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- COMT (Catechol-O-Methyltransferase (COMT))
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Andere Bezeichnung
- COMT
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Hintergrund
- Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.
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Gen-ID
- 1312
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UniProt
- P21964
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Pathways
- Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interaktom
Target
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