SLC40A1 Antikörper

Produktnummer ABIN701095

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SLC40A1 in WB, IHC (p) und IF (p). Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund und Schwein.

Kurzübersicht für SLC40A1 Antikörper (ABIN701095)

Target: SLC40A1 (Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1 (SLC40A1))

Reaktivität: Human, Maus, Ratte, Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC40A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-SLC40A1 Antikörper

Kreuzreaktivität: Hund, Human, Maus, Schwein, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SLC40A1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:100-500)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu SLC40A1

Target: SLC40A1 (Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1 (SLC40A1))

Andere Bezeichnung: SLC40A1

Hintergrund:

Synonyms: Ferroportin 1, Ferroportin-1, FPN1, HFE4, IREG1, Iron regulated transporter 1, Iron-regulated transporter 1, MTP1, S40A1_HUMAN, SLC40A1, Solute carrier family 40 member 1, MST079, MSTP079, MTP1, SLC11A3.

Background: SLC40A1 may be involved in iron export from duodenal epithelial cells and also in transfer of iron between maternal and fetal circulation. It mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin). Defects in SLC40A1 are the cause of hemochromatosis type 4, an autosomal dominant iron-loading disorder characterized by early iron accumulation in reticuloendothelial cells and a marked increase in serum ferritin.

Molekulargewicht: 63kDa

Gen-ID: 30061

Pathways: Transition Metal Ion Homeostasis