SLC40A1 Antikörper

Produktnummer ABIN701095

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SLC40A1 in WB, IHC (p) und IF (p). Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Hund und Schwein.

Kurzübersicht für SLC40A1 Antikörper (ABIN701095)

Target: SLC40A1 (Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1 (SLC40A1))

Reaktivität: Human, Maus, Ratte, Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC40A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-SLC40A1 Antikörper

Kreuzreaktivität: Hund, Human, Maus, Schwein, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SLC40A1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:100-500)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu SLC40A1

Target: SLC40A1 (Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1 (SLC40A1))

Andere Bezeichnung: SLC40A1

Hintergrund:

Synonyms: Ferroportin 1, Ferroportin-1, FPN1, HFE4, IREG1, Iron regulated transporter 1, Iron-regulated transporter 1, MTP1, S40A1_HUMAN, SLC40A1, Solute carrier family 40 member 1, MST079, MSTP079, MTP1, SLC11A3.

Background: SLC40A1 may be involved in iron export from duodenal epithelial cells and also in transfer of iron between maternal and fetal circulation. It mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin). Defects in SLC40A1 are the cause of hemochromatosis type 4, an autosomal dominant iron-loading disorder characterized by early iron accumulation in reticuloendothelial cells and a marked increase in serum ferritin.

Molekulargewicht: 63kDa

Gen-ID: 30061

Pathways: Transition Metal Ion Homeostasis