BAF53A Antikörper

Produktnummer ABIN7261339

Der Kaninchen Polyklonal Anti-BAF53A-Antikörper wurde für WB validiert. Er ist geeignet, BAF53A in Proben von Human und Maus zu detektieren.

Kurzübersicht für BAF53A Antikörper (ABIN7261339)

Target: BAF53A (Actin-Like 6A (BAF53A))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAF53A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BAF53A Antikörper

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human ACTL6A (NP_004292.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu BAF53A

Target: BAF53A (Actin-Like 6A (BAF53A))

Andere Bezeichnung: ACTL6A

Hintergrund: This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila, the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.

Molekulargewicht:

Observed_MW: 48 kDa

Calculated_MW: 43 kDa/47 kDa

Gen-ID: 86

UniProt: O96019

Pathways: Chromatin Binding, Photoperiodism