RBM15 Antikörper

Produktnummer ABIN7261163

This anti-RBM15 antibody (ABIN7261163) is a Rabbit Polyclonal antibody detecting RBM15 in WB. Suitable for Human, Mouse.

Kurzübersicht für RBM15 Antikörper (ABIN7261163)

Target: RBM15 (RNA Binding Motif Protein 15 (RBM15))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RBM15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RBM15 Antikörper

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human RBM15 (NP_001188474.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RBM15

Target: RBM15 (RNA Binding Motif Protein 15 (RBM15))

Andere Bezeichnung: RBM15

Hintergrund: RNA-binding motif protein 15 (RBM15) belongs to the SPEN protein family,which have repressor function in several signaling pathway,and may bind to RNA through interaction with spliceosome components. It was first described as a 5' translocation partner of the MAL gene in t(1,22)(p13,q13) infant acute megakaryocytic leukemia,and it functions in murine hematopoiesis through modulating Notch-induced transcriptional activation,which play crucial roles in leukemogenesis. Decreasing RBM15 levels with RNA interference could inhibit the growth and proliferation,block the cell cycle,and induce apoptosis in CML cells.

Molekulargewicht:

Observed_MW: 120 kDa

Calculated_MW: 99 kDa/104 kDa/106 kDa/107 kDa

Gen-ID: 64783

UniProt: Q96T37