PGC Antikörper

Produktnummer ABIN7260655

Dieses Anti-PGC-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PGC in WB. Geeignet für Human, Ratte und Maus.

Kurzübersicht für PGC Antikörper (ABIN7260655)

Target: PGC (Pepsinogen C (PGC))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PGC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PGC Antikörper

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide of human Pepsinogen II (NP_001159896.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PGC

Target: PGC (Pepsinogen C (PGC))

Andere Bezeichnung: Pepsinogen II

Hintergrund: This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.

Molekulargewicht:

Observed_MW: 45-50 kDa

Calculated_MW: 34 kDa/42 kDa

Gen-ID: 5225

UniProt: P20142