Der Kaninchen Polyklonal Anti-ABCB8-Antikörper wurde für IHC und IF validiert. Er ist geeignet, ABCB8 in Proben von Human, Maus und Ratte zu detektieren.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
ABCB8
(ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 8 (ABCB8))
Andere Bezeichnung
ABCB8
Hintergrund
This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants.