DMAP1 Antikörper

Produktnummer ABIN7260348

Dieses Anti-DMAP1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DMAP1 in WB. Geeignet für Human, Maus und Ratte.

Kurzübersicht für DMAP1 Antikörper (ABIN7260348)

Target: DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DMAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DMAP1 Antikörper

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human DMAP1 (NP_061973.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-1:4000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DMAP1

Target: DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

Andere Bezeichnung: DMAP1

Hintergrund: This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.

Molekulargewicht:

Observed_MW: 60 kDa

Calculated_MW: 52 kDa

Gen-ID: 55929

UniProt: Q9NPF5