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FKBP1A Antikörper

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FKBP1A in IHC. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN7259707

Kurzübersicht für FKBP1A Antikörper (ABIN7259707)

Target

Alle FKBP1A Antikörper anzeigen
FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Reaktivität

  • 68
  • 29
  • 21
  • 7
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 64
  • 13
Kaninchen

Klonalität

  • 55
  • 22
Polyklonal

Konjugat

  • 36
  • 10
  • 10
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Dieser FKBP1A Antikörper ist unkonjugiert

Applikation

  • 48
  • 30
  • 19
  • 16
  • 14
  • 11
  • 9
  • 5
  • 3
  • 2
  • 1
  • 1
Immunohistochemistry (IHC)
  • Produktmerkmale

    Polyclonal Antibody

    Aufreinigung

    Affinity purification

    Immunogen

    Recombinant fusion protein of human FKBP1A (NP_463460.1).

    Isotyp

    IgG
  • Applikationshinweise

    IHC 1:50-1:200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

    Andere Bezeichnung

    FKBP1A

    Hintergrund

    The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed.

    Gen-ID

    2280

    UniProt

    P62942

    Pathways

    Negative Regulation of Transporter Activity, Methionine Biosynthetic Process
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