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MBP Antikörper

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MBP in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN7259298

Kurzübersicht für MBP Antikörper (ABIN7259298)

Target

Alle MBP Antikörper anzeigen
MBP (Myelin Basic Protein (MBP))

Reaktivität

  • 124
  • 37
  • 36
  • 21
  • 13
  • 11
  • 8
  • 6
  • 6
  • 5
  • 5
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 88
  • 38
  • 10
  • 6
  • 5
  • 1
Kaninchen

Klonalität

  • 93
  • 52
  • 1
Polyklonal

Konjugat

  • 100
  • 10
  • 7
  • 7
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MBP Antikörper ist unkonjugiert

Applikation

  • 98
  • 64
  • 42
  • 34
  • 26
  • 17
  • 11
  • 11
  • 7
  • 7
  • 6
  • 5
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Produktmerkmale

    Polyclonal Antibody

    Aufreinigung

    Affinity purification

    Immunogen

    Recombinant fusion protein of human Myelin Basic protein (NP_001020271.1).

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:500-1:2000 IHC 1:50-1:200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    MBP (Myelin Basic Protein (MBP))

    Andere Bezeichnung

    Myelin Basic protein

    Hintergrund

    The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called 'Golli-MBP') that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes.

    Molekulargewicht

    Observed_MW: 17 kDa/33 kDa/40 kDa

    Calculated_MW: 17 kDa/18 kDa/20 kDa/21 kDa/33 kDa

    Gen-ID

    4155

    UniProt

    P02686
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