FREM1 Antikörper

Produktnummer ABIN7259276

Produktdetails anti-FREM1 Antikörper

Target: FREM1 (FRAS1 Related Extracellular Matrix 1 (FREM1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FREM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human FREM1 (NP_659403.4).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu FREM1

Target: FREM1 (FRAS1 Related Extracellular Matrix 1 (FREM1))

Andere Bezeichnung: FREM1 (FREM1 Produkte)

Synonyme: BNAR antikoerper, C9orf143 antikoerper, C9orf145 antikoerper, C9orf154 antikoerper, MOTA antikoerper, TILRR antikoerper, TRIGNO2 antikoerper, RGD1306981 antikoerper, BC037594 antikoerper, D430009N09 antikoerper, D630008K06 antikoerper, eye antikoerper, eyes2 antikoerper, heb antikoerper, qbrick antikoerper, FRAS1 related extracellular matrix 1 antikoerper, Fras1 related extracellular matrix 1 antikoerper, Fras1 related extracellular matrix protein 1 antikoerper, FREM1 antikoerper, Frem1 antikoerper

Hintergrund: This gene encodes a basement membrane protein that may play a role in craniofacial and renal development. Mutations in this gene have been associated with bifid nose with or without anorectal and renal anomalies. Alternatively spliced transcript variants encoding different isoforms have been described. PubMed ID 19940113 describes one such variant that initiates transcription within a distinct, internal exon, the resulting shorter isoform (named Toll-like/interleukin-1 receptor regulator, TILRR) is suggested to be a co-receptor of the interleukin 1 receptor family and may regulate receptor function and Toll-like receptor/interleukin 1 receptor signal transduction, contributing to the control of inflammatory response activation.

Molekulargewicht:

Observed_MW: 72 kDa

Calculated_MW: 25 kDa/42 kDa/80 kDa/244 kDa

Gen-ID: 158326

UniProt: Q5H8C1