FREM1 Antikörper

Produktnummer ABIN7259276

Der Kaninchen Polyklonal Anti-FREM1-Antikörper wurde für WB validiert. Er ist geeignet, FREM1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für FREM1 Antikörper (ABIN7259276)

Target: FREM1 (FRAS1 Related Extracellular Matrix 1 (FREM1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FREM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FREM1 Antikörper

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human FREM1 (NP_659403.4).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu FREM1

Target: FREM1 (FRAS1 Related Extracellular Matrix 1 (FREM1))

Andere Bezeichnung: FREM1

Hintergrund: This gene encodes a basement membrane protein that may play a role in craniofacial and renal development. Mutations in this gene have been associated with bifid nose with or without anorectal and renal anomalies. Alternatively spliced transcript variants encoding different isoforms have been described. PubMed ID 19940113 describes one such variant that initiates transcription within a distinct, internal exon, the resulting shorter isoform (named Toll-like/interleukin-1 receptor regulator, TILRR) is suggested to be a co-receptor of the interleukin 1 receptor family and may regulate receptor function and Toll-like receptor/interleukin 1 receptor signal transduction, contributing to the control of inflammatory response activation.

Molekulargewicht:

Observed_MW: 72 kDa

Calculated_MW: 25 kDa/42 kDa/80 kDa/244 kDa

Gen-ID: 158326

UniProt: Q5H8C1