ASCC1 Antikörper

Produktnummer ABIN7258728

Dieses Anti-ASCC1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ASCC1 in WB. Geeignet für Human, Maus und Ratte.

Kurzübersicht für ASCC1 Antikörper (ABIN7258728)

Target: ASCC1 (Activating Signal Cointegrator 1 Complex Subunit 1 (ASCC1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ASCC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ASCC1 Antikörper

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human ASCC1 (NP_001185727.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ASCC1

Target: ASCC1 (Activating Signal Cointegrator 1 Complex Subunit 1 (ASCC1))

Andere Bezeichnung: ASCC1

Hintergrund: This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.

Molekulargewicht:

Observed_MW: 46 kDa

Calculated_MW: 41 kDa/45 kDa

Gen-ID: 51008

UniProt: Q8N9N2