Reticulon 3 Antikörper
Kurzübersicht für Reticulon 3 Antikörper (ABIN7258404)
Target
Alle Reticulon 3 (RTN3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Produktmerkmale
- Polyclonal Antibody
-
Aufreinigung
- Affinity purification
-
Immunogen
- A synthetic peptide of human RTN3 (NP_006045.1).
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB 1:500-1:2000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- Reticulon 3 (RTN3)
-
Andere Bezeichnung
- RTN3
-
Hintergrund
- This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12.
-
Molekulargewicht
-
Observed_MW: 26 kDa
Calculated_MW: 23 kDa/25 kDa/26 kDa/27 kDa/100 kDa/110 kDa/112 kDa
-
Gen-ID
- 10313
-
UniProt
- O95197
Target
-