DDX3Y Antikörper

Produktnummer ABIN7258146

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch DDX3Y in WB. Er zeigt eine Reaktivität gegenüber Human und Ratte.

Kurzübersicht für DDX3Y Antikörper (ABIN7258146)

Target: DDX3Y (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, Y-Linked (DDX3Y))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DDX3Y Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DDX3Y Antikörper

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human DDX3Y (NP_001116137.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DDX3Y

Target: DDX3Y (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, Y-Linked (DDX3Y))

Andere Bezeichnung: DDX3Y

Hintergrund: The protein encoded by this gene is a member of the DEAD-box RNA helicase family, characterized by nine conserved motifs, included the conserved Asp-Glu-Ala-Asp (DEAD) motif. These motifs are thought to be involved in ATP binding, hydrolysis, RNA binding, and in the formation of intramolecular interactions. This protein shares high similarity to DDX3X, on the X chromosome, but a deletion of this gene is not complemented by DDX3X. Mutations in this gene result in male infertility, a reduction in germ cell numbers, and can result in Sertoli-cell only sydrome. Pseudogenes sharing similarity to both this gene and the DDX3X paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht:

Observed_MW: 73 kDa

Calculated_MW: 32 kDa/72 kDa/73 kDa

Gen-ID: 8653

UniProt: O15523