SNAP23 Antikörper

Produktnummer ABIN7257463

Produktdetails anti-SNAP23 Antikörper

Target: SNAP23 (Synaptosomal-Associated Protein, 23kDa (SNAP23))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNAP23 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human SNAP23 (NP_003816.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SNAP23

Target: SNAP23 (Synaptosomal-Associated Protein, 23kDa (SNAP23))

Andere Bezeichnung: SNAP23 (SNAP23 Produkte)

Synonyme: 23kDa antikoerper, AA408749 antikoerper, SNAP-23 antikoerper, Sndt antikoerper, Syndet antikoerper, HsT17016 antikoerper, SNAP23A antikoerper, SNAP23B antikoerper, XOSNAP-23 antikoerper, snap23-A antikoerper, synaptosome associated protein 23 antikoerper, synaptosome associated protein 23kDa antikoerper, synaptosomal-associated protein 23 antikoerper, synaptosome associated protein 23kDa L homeolog antikoerper, SNAP23 antikoerper, snap23 antikoerper, Snap23 antikoerper, snap23.L antikoerper

Hintergrund: Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene.

Gen-ID: 8773

UniProt: O00161