CAMLG Antikörper
Kurzübersicht für CAMLG Antikörper (ABIN7257333)
Target
Alle CAMLG Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein of human CAMLG (NP_001736.1).
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- CAMLG (Calcium Modulating Ligand (CAMLG))
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Andere Bezeichnung
- CAMLG
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Hintergrund
- The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.
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Molekulargewicht
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Observed_MW: 38 kDa
Calculated_MW: 32 kDa
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Gen-ID
- 819
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UniProt
- P49069
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Pathways
- EGFR Signaling Pathway
Target
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