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GCSH Antikörper

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GCSH in WB und IF. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN7257311

Kurzübersicht für GCSH Antikörper (ABIN7257311)

Target

Alle GCSH Antikörper anzeigen
GCSH (Glycine Cleavage System H Protein (GCSH))

Reaktivität

  • 39
  • 10
  • 10
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 37
  • 2
Kaninchen

Klonalität

  • 38
  • 1
Polyklonal

Konjugat

  • 13
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser GCSH Antikörper ist unkonjugiert

Applikation

  • 31
  • 15
  • 13
  • 13
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF)
  • Produktmerkmale

    Polyclonal Antibody

    Aufreinigung

    Affinity purification

    Immunogen

    Recombinant fusion protein of human GCSH (NP_004474.2).

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:500-1:2000 IF 1:50-1:200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    GCSH (Glycine Cleavage System H Protein (GCSH))

    Andere Bezeichnung

    GCSH

    Hintergrund

    Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.

    Molekulargewicht

    Observed_MW: 19 kDa

    Calculated_MW: 18 kDa

    Gen-ID

    2653

    UniProt

    P23434
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