CD1d Antikörper

Produktnummer ABIN7257038

Der Kaninchen Polyklonal Anti-CD1d-Antikörper wurde für WB, IHC und IF validiert. Er ist geeignet, CD1d in Proben von Maus und Human zu detektieren.

Kurzübersicht für CD1d Antikörper (ABIN7257038)

Target: CD1d (CD1D) (CD1d Molecule (CD1D))

Reaktivität: Maus, Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD1d Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-CD1d Antikörper

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human CD1D (NP_001757.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CD1d

Target: CD1d (CD1D) (CD1d Molecule (CD1D))

Andere Bezeichnung: CD1D

Hintergrund: This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Two transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht:

Observed_MW: 35 kDa

Calculated_MW: 37 kDa

Gen-ID: 912

UniProt: P15813

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process